Weight Change across Adulthood in Relation to Non-Alcoholic Fatty Liver Disease among Non-Obese Individuals.

ABSTRACT:

Background

To investigate the associations of weight change patterns across adulthood with the risk of non-alcoholic fatty liver disease (NAFLD).

Methods

Using data from the National Health and Nutrition Examination Survey (NHANES) 2017-2018 cycle, we performed a retrospective cohort study with 2212 non-obese participants aged 36 years old over. Weight change patterns were categorized as "stable non-obese", "early adulthood weight gain", "middle and late adulthood weight gain" and "revert to non-obese" according to the body mass index (BMI) at age 25, 10 years prior and at baseline. Vibration-controlled transient elastography (VCTE) was performed to diagnose NAFLD. Modified Poisson regression was used to quantify the associations of weight change patterns with NAFLD.

Resu

SUBMITTER: Ding Y 

PROVIDER: S-EPMC9144793 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature