Microfluidics Temperature Compensating and Monitoring Based on Liquid Metal Heat Transfer.

ABSTRACT: Microfluidic devices offer excellent heat transfer, enabling the biochemical reactions to be more efficient. However, the precision of temperature sensing and control of microfluids is limited by the size effect. Here in this work, the relationship between the microfluids and the glass substrate of a typical microfluidic device is investigated. With an intelligent structure design and liquid metal, we demonstrated that a millimeter-scale industrial temperature sensor could be utilized for temperature sensing of micro-scale fluids. We proposed a heat transfer model based on this design, where the local correlations between the macro-scale temperature sensor and the micro-scale fluids were investigated. As a demonstration, a set of temperature-sensitive nucleic acid amplification tests were

SUBMITTER: Meng J 

PROVIDER: S-EPMC9146403 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature