Effects of Exercise and Physical Activity Levels on Vaccination Efficacy: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

We examined whether different intensities of exercise and/or physical activity (PA) levels affected and/or associated with vaccination efficacy.

Methods

A systematic review and meta-analysis was conducted and registered with PROSPERO (CRD42021230108). The PubMed, EMBASE, Cochrane Library (trials), SportDiscus, and CINAHL databases were searched up to January 2022.

Results

In total, 38 eligible studies were included. Chronic exercise increased influenza antibodies (standardized mean difference (SMD) = 0.49, confidence interval (CI) = 0.25-0.73, Z = 3.95, I² = 90%, p < 0.01), which was mainly driven by aerobic exercise (SMD = 0.39, CI = 0.19-0.58, Z = 3.96, I² = 77%, p < 0.01) as opposed to combined (aerobic + resistan

SUBMITTER: Dinas PC 

PROVIDER: S-EPMC9146578 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature