Liver disease in cystic fibrosis patients in a tertiary care center in Saudi Arabia.

ABSTRACT:

Background

Internationally, Cystic fibrosis-associated liver disease (CFLD) is considered the third leading cause of death, following lung disease and transplantation complications.

Aims

To identify the prevalence of CFLD in cystic fibrosis (CF) patients.

Methodology

A retrospective chart review for all patients with CF liver disease from a tertiary care center.

Result

A total of 341 CF patients were included. The mean age at the diagnosis of liver disease is 13.5 (7.6) years.The first elevated ALT was reported in 190/341 patients (56%), elevated AST in 124 patients (36%), elevated alkaline phosphatase (ALP) in 166 patients (49.1%), elevated GGT in 57 patients (23%), and elevated bilirubin in 24 patients (7%). There was an improvement of the liver enzyme values

SUBMITTER: Banjar H 

PROVIDER: S-EPMC9152554 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature