A brain atlas of axonal and synaptic delays based on modelling of cortico-cortical evoked potentials.

ABSTRACT: Epilepsy presurgical investigation may include focal intracortical single-pulse electrical stimulations with depth electrodes, which induce cortico-cortical evoked potentials at distant sites because of white matter connectivity. Cortico-cortical evoked potentials provide a unique window on functional brain networks because they contain sufficient information to infer dynamical properties of large-scale brain connectivity, such as preferred directionality and propagation latencies.  Here, we developed a biologically informed modelling approach to estimate the neural physiological parameters of brain functional networks from the cortico-cortical evoked potentials recorded in a large multicentric database. Specifically, we considered each cortico-cortical evoked potential as the output of a

SUBMITTER: Lemarechal JD 

PROVIDER: S-EPMC9166555 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature