Ontology highlight
ABSTRACT:
SUBMITTER: Zhu XW
PROVIDER: S-EPMC9167983 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Zhu Xiao-Wei XW Liu Ke-Qi KQ Yuan Cheng-Da CD Xia Jiang-Wei JW Qian Yu Y Xu Lin L Gao Jian-Hua JH Rong Xiao-Li XL Chen Guo-Bo GB Karasik David D Xie Shu-Yang SY Zheng Hou-Feng HF
iScience 20220525 6
To infer the causality between obesity and fracture and the difference between general and abdominal obesity, a prospective study was performed in 456,921 participants, and 10,142 participants developed an incident fracture with follow-up period of 7.96 years. A U-shape relationship was observed between BMI and fracture, with the lowest risk of fracture in overweight participants. The obesity individuals had higher fracture risk when BMD was adjusted, and the protective effect of moderate-high B ...[more]