Gastro-oesophageal reflux and worse asthma control in obese children: a case of symptom misattribution?

ABSTRACT:

Background

Obese children for unknown reasons report greater asthma symptoms. Asthma and obesity both independently associate with gastro-oesophageal reflux symptoms (GORS). Determining if obesity affects the link between GORS and asthma will help elucidate the obese-asthma phenotype.

Objective

Extend our previous work to determine the degree of associations between the GORS and asthma phenotype.

Methods

We conducted a cross-sectional study of lean (20%-65% body mass index, BMI) and obese (≥95% BMI) children aged 10-17 years old with persistent, early-onset asthma. Participants contributed demographics, GORS and asthma questionnaires and lung function data. We determined associations between weight status, GORS and asthma outcomes using multivariable linear and logist

SUBMITTER: Lang JE 

PROVIDER: S-EPMC9169159 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature