Exposure to Chloramine and Chloroform in Tap Water and Adverse Perinatal Outcomes in Shanghai.

ABSTRACT: Chloramine and chloroform are widespread in tap water due to water disinfection processes. This study was designed to explore the associations between trimester-specific exposure to chloramine and chloroform in tap water and adverse outcomes. This retrospective cohort study included 109,182 mother-infant singleton pairs in Shanghai. A logistic regression model was used to evaluate the associations of chloramine and chloroform concentrations averaged over the whole pregnancy and in each trimester with adverse outcomes, including gestational diabetes mellitus (GDM), gestational hypertensive disorders (GHD), low birthweight (LBW), small for gestational age (SGA), preterm birth (PTB) and prelabor rupture of membranes (PROM). The use of tap water with elevated chloramine levels in the first tri

SUBMITTER: Zhu SM 

PROVIDER: S-EPMC9180198 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature