Dataset Information

Simulation Study of Radio Frequency Safety and the Optimal Size of a Single-Channel Surface Radio Frequency Coil for Mice at 9.4 T Magnetic Resonance Imaging.

ABSTRACT: The optimized size of a single-channel surface radio frequency (RF) coil for mouse body images in a 9.4 T magnetic resonance imaging (MRI) system was determined via electromagnetic-field analysis of the signal depth according to the size of a single-channel coil. The single-channel surface RF coils used in electromagnetic field simulations were configured to operate in transmission/reception mode at a frequency of 9.4 T-400 MHz. Computational analysis using the finite-difference time-domain method was used to assess the single-channel surface RF coil by comparing single-channel surface RF coils of varying sizes in terms of |B₁|-, |B₁⁺|-, |B₁^-|- and |E|-field distribution. RF safety for the prevention of burn injuries to small animals was assessed using an analysis of the specific absorption rate. A single-channel surface RF coil with a 20 mm diameter provided optimal B₁-field distribution and RF safety, thus confirming that single-channel surface RF coils with ≥25 mm diameter could not provide typical B₁-field distribution. A single-channel surface RF coil with a 20 mm diameter for mouse body imaging at 9.4 T MRI was recommended to preserve the characteristics of single-channel surface RF coils, and ensured that RF signals were applied correctly to the target point within RF safety guidelines.

SUBMITTER: Seo JH

PROVIDER: S-EPMC9185248 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Publications

Simulation Study of Radio Frequency Safety and the Optimal Size of a Single-Channel Surface Radio Frequency Coil for Mice at 9.4 T Magnetic Resonance Imaging.

Seo Jeung-Hoon JH Ryu Yeunchul Y Chung Jun-Young JY

Sensors (Basel, Switzerland) 20220603 11

The optimized size of a single-channel surface radio frequency (RF) coil for mouse body images in a 9.4 T magnetic resonance imaging (MRI) system was determined via electromagnetic-field analysis of the signal depth according to the size of a single-channel coil. The single-channel surface RF coils used in electromagnetic field simulations were configured to operate in transmission/reception mode at a frequency of 9.4 T-400 MHz. Computational analysis using the finite-difference time-domain meth ...[more]

PMID: 35684895

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Project description:BackgroundWe aimed to demonstrate the feasibility of generating high-resolution human brain magnetic resonance imaging (MRI) at 5 Tesla (T) using a quadrature birdcage transmit/48-channel receiver coil assembly.MethodsA quadrature birdcage transmit/48-channel receiver coil assembly was designed for human brain imaging at 5T. The radio frequency (RF) coil assembly was validated by electromagnetic (EM) simulations and phantom imaging experimental studies. The simulated B1+ field inside a human head phantom and inside a human head model generated by the birdcage coils driven in circularly polarized (CP) mode at 3T, 5T and 7T was compared. Signal-to-noise ratio (SNR) maps, the inverse g-factor maps for evaluation of parallel imaging performance, anatomic images, angiography images, vessel wall images and susceptibility weighted images (SWI) were acquired using the RF coil assembly at 5T and compared to those acquired using a 32-channel head coil on a 3T MRI scanner.ResultsFor the EM simulations, 5T MRI provided less RF inhomogeneity compared to that of 7T. In the phantom imaging study, the distributions of the measured B1+ field were consistent with the distributions of the simulated B1+ field. In the human brain imaging study, the average SNR value of the brain in the transversal plane at 5T was 1.6 times of that at 3T. The 48-channel head coil at 5T had higher parallel acceleration capability than the 32-channel head coil at 3T. The anatomic images at 5T also showed higher SNR than those at 3T. Improved delineation of the hippocampus, lenticulostriate arteries, and basilar arteries was observed at 5T compared to 3T. SWI with a higher resolution of 0.3 mm ×0.3 mm ×1.2 mm could be acquired at 5T, which enabled better visualization of small blood vessels compared to that at 3T.Conclusions5T MRI can provide significant SNR improvement compared to that of 3T with less RF inhomogeneity than that of 7T. The ability to obtain high quality in vivo human brain images at 5T using the quadrature birdcage transmit/48-channel receiver coil assembly has significant in clinical and scientific research applications.

Dataset Information

Simulation Study of Radio Frequency Safety and the Optimal Size of a Single-Channel Surface Radio Frequency Coil for Mice at 9.4 T Magnetic Resonance Imaging.

Publications

Simulation Study of Radio Frequency Safety and the Optimal Size of a Single-Channel Surface Radio Frequency Coil for Mice at 9.4 T Magnetic Resonance Imaging.

Similar Datasets

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