High-Altitude Erythrocytosis: Mechanisms of Adaptive and Maladaptive Responses.
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ABSTRACT:
SUBMITTER: Villafuerte FC
PROVIDER: S-EPMC9191173 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
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High-Altitude Erythrocytosis: Mechanisms of Adaptive and Maladaptive Responses.
Villafuerte Francisco C FC Simonson Tatum S TS Bermudez Daniela D León-Velarde Fabiola F
Physiology (Bethesda, Md.) 20220110 4
Erythrocytosis, or increased production of red blood cells, is one of the most well-documented physiological traits that varies within and among in high-altitude populations. Although a modest increase in blood O<sub>2</sub>-carrying capacity may be beneficial for life in highland environments, erythrocytosis can also become excessive and lead to maladaptive syndromes such as chronic mountain sickness (CMS). ...[more]
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