The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function: A Preliminary Report.
Ontology highlight
ABSTRACT: Background
Serotonin plays an important role in mood regulation and depression. However, it is not clear whether the levels of serotonin in saliva are related to current mood.Aim
To test the association of salivary serotonin concentrations with mood, as well as cardiovascular and autonomic parameters.Materials and methods
Saliva samples were obtained from collegiate runners and output parameters were examined before and after physical activity.Results
Salivary serotonin concentration was negatively associated with current mood (β = -0.32, 95%CI -0.62 to -0.02, p = 0.037, analysis adjusted for potential confounders), but insignificantly with measured cardiovascular and autonomic parameters.Conclusions
Salivary serotonin may reflect current mood. The results are preliminary and require further evaluation.
SUBMITTER: Karbownik MS
PROVIDER: S-EPMC9193578 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
The Association of Salivary Serotonin With Mood and Cardio-Autonomic Function: A Preliminary Report.
Karbownik Michał Seweryn MS Hicks Steven Daniel SD
Frontiers in psychiatry 20220531
<h4>Background</h4>Serotonin plays an important role in mood regulation and depression. However, it is not clear whether the levels of serotonin in saliva are related to current mood.<h4>Aim</h4>To test the association of salivary serotonin concentrations with mood, as well as cardiovascular and autonomic parameters.<h4>Materials and methods</h4>Saliva samples were obtained from collegiate runners and output parameters were examined before and after physical activity.<h4>Results</h4>Salivary ser ...[more]
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