Brain functional connectivity in children with developmental coordination disorder following rehabilitation intervention.

ABSTRACT:

Background

Children with developmental coordination disorder (DCD) show improved motor function after Cognitive Orientation to Occupational Performance (CO-OP) intervention; however, the neural basis for these improvements is unknown.

Methods

In this randomized waitlist-controlled trial, 78 children with DCD (with/without ADHD) were randomly assigned to either a treatment or waitlist group and underwent three resting-state MRI scans over six months. The treatment group received intervention between the first and second scan; the waitlist group received intervention between the second and third scan.

Results

After CO-OP intervention, children with DCD [13 male, 8 female; mean (SD) age: 10.0 (1.7) years] showed increased functional connectivity between the default mode

SUBMITTER: Izadi-Najafabadi S 

PROVIDER: S-EPMC9197764 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature