Factors associated with TNF-alpha levels in patients with indirect inguinal hernia: A cross-sectional study.

ABSTRACT:

Introduction

Risk factors associated with inguinal hernia include a patent processus vaginalis due to an obliteration failure, defects in the transversalis fascia, increased intra-abdominal pressure, smoking, malnutrition, genetic factors, connective tissue defects and impaired collagen metabolism. Type I collagen predominates in the fascia, which plays a key role in the development of an inguinal hernia. Molecularly, the production of abnormal matrix components or increased inflammatory mediators in collagen such as TNF-α has a very important role in the occurrence of inflammation in inguinal hernias. The study aimed to determine the factors associated with TNF-alpha levels in patients with indirect inguinal hernias.

Methods

We evaluate the effect of TNF-α on the anterior r

SUBMITTER: Warsinggih 

PROVIDER: S-EPMC9207110 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature