Ten-year trends and prediction model of 30-day inpatient mortality for alcoholic hepatitis in the United States.

ABSTRACT:

Background

Alcoholic hepatitis (AH) results in significant morbidity, mortality and healthcare burden. We aimed to evaluate the temporal trends of AH hospitalizations in the last decade and to devise a mortality scoring system for risk stratification.

Methods

National Inpatient Sample (NIS) databases from 2009-2019 were used to identify AH hospitalizations. Outcomes of interest included temporal trend analysis of length of stay (LOS), mean inpatient cost (MIC), mortality, and mortality predictors. A mortality scoring system was derived using multivariate Cox regression and validated using receiver operating characteristic curves.

Results

There was an increase in total AH hospitalizations, from 67,070 in 2009 to 125,540 in 2019 (P=0.004). The inpatient mortality increa

SUBMITTER: Ali H 

PROVIDER: S-EPMC9210782 | biostudies-literature | 2022 Jul-Aug

REPOSITORIES: biostudies-literature