Multicomponent Strategy with Decentralized Molecular Testing for Tuberculosis.

ABSTRACT:

Background

Effective strategies are needed to facilitate the prompt diagnosis and treatment of tuberculosis in countries with a high burden of the disease.

Methods

We conducted a cluster-randomized trial in which Ugandan community health centers were assigned to a multicomponent diagnostic strategy (on-site molecular testing for tuberculosis, guided restructuring of clinic workflows, and monthly feedback of quality metrics) or routine care (on-site sputum-smear microscopy and referral-based molecular testing). The primary outcome was the number of adults treated for confirmed tuberculosis within 14 days after presenting to the health center for evaluation during the 16-month intervention period. Secondary outcomes included completion of tuberculosis testing, same-day diagnos

SUBMITTER: Cattamanchi A 

PROVIDER: S-EPMC9212879 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature