J wave syndromes in patients with spinal and bulbar muscular atrophy.

ABSTRACT:

Background

Males with X-linked recessive spinobulbar muscular atrophy (SBMA) are reported to die suddenly and a Brugada electrocardiography (ECG) pattern may be present. A hallmark of this pattern is the presence of ST segment elevations in right precordial leads associated with an increased risk of sudden cardiac death.

Objective

We aimed to detect subtle myocardial abnormalities using ECG and cardiovascular magnetic resonance imaging (CMR) in patients with SBMA.

Methods

30 SBMA patients (55.7 ± 11.9 years) and 11 healthy male controls underwent 12-lead ECGs were recorded using conventional and modified chest leads. CMR included feature-tracking strain analysis, late gadolinium enhancement and native T1 and T2 mapping.

Results

Testosterone levels were increase

SUBMITTER: Steinmetz K 

PROVIDER: S-EPMC9217903 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature