Long-term exposure to fine particulate matter and ozone and the onset of systemic autoimmune rheumatic diseases: an open cohort study in Quebec, Canada.

ABSTRACT:

Objectives

To estimate associations between fine particulate matter (PM_2.5) and ozone and the onset of systemic autoimmune rheumatic diseases (SARDs).

Methods

An open cohort of over 6 million adults was constructed from provincial physician billing and hospitalization records between 2000 and 2013. We defined incident SARD cases (SLE, Sjogren's syndrome, scleroderma, polymyositis, dermatomyositis, polyarteritis nodosa and related conditions, polymyalgia rheumatic, other necrotizing vasculopathies, and undifferentiated connective tissue disease) based on at least two relevant billing diagnostic codes (within 2 years, with at least 1 billing from a rheumatologist), or at least one relevant hospitalization diagnostic code. Estimated PM_2.5 and ozone concent

SUBMITTER: Zhao N 

PROVIDER: S-EPMC9219240 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature