Dataset Information

Functional Capacity in Patients Who Recovered from Mild COVID-19 with Exertional Dyspnea.

ABSTRACT:

Background

Post mild COVID-19 dyspnea is poorly understood. We assessed physiologic limitations in these patients.

Methods

Patients with post mild COVID-19 dyspnea (group A) were compared (pulmonary function tests, 6-min walk test (6MWT), echocardiography and cardiopulmonary exercise test (CPET)) to post moderate/severe COVID-19 (group B) and to CPET and spirometry of patients with unexplained dyspnea (group C).

Results

The study included 36 patients (13 in A, 9 in B and 14 in C). Diffusion capacity was lower in group B compared to group A (64 ± 8 vs. 85 ± 9% predicted, p = 0.014). 6MWT was normal and similar in both patient groups. Oxygen uptake was higher in group A compared to groups B and C (108 ± 14 vs. 92 ± 13 and 91 ± 23% predicted, p = 0.013, 0.03, respectively). O₂ pulse was normal in all three groups but significantly higher in the mild group compared to the control group. Breathing reserve was low/borderline in 2/13 patients in the mild group, 2/9 in the moderate/severe group and 3/14 in the control group (NS).

Conclusions

Patients with post mild COVID-19 dyspnea had normal CPET, similar to patients with unexplained dyspnea. Other mechanisms should be investigated and the added value of CPET to patients with post mild COVID-19 dyspnea is questionable.

SUBMITTER: Dotan Y

PROVIDER: S-EPMC9224561 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Publications

Functional Capacity in Patients Who Recovered from Mild COVID-19 with Exertional Dyspnea.

Dotan Yaniv Y Weiner Elite E Zucker-Toledano Merav M Solomonov Anna A Fuchs Eyal E Dawood Hanna H Mor Elad E Hanna Moneera M Naser-Aldeen Rihan R Bentur Lea L Bar-Yoseph Ronen R

Journal of personalized medicine 20220526 6

<h4>Background</h4>Post mild COVID-19 dyspnea is poorly understood. We assessed physiologic limitations in these patients.<h4>Methods</h4>Patients with post mild COVID-19 dyspnea (group A) were compared (pulmonary function tests, 6-min walk test (6MWT), echocardiography and cardiopulmonary exercise test (CPET)) to post moderate/severe COVID-19 (group B) and to CPET and spirometry of patients with unexplained dyspnea (group C).<h4>Results</h4>The study included 36 patients (13 in A, 9 in B and 14 ...[more]

PMID: 35743659

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Project description:Due to the currently ongoing pandemic of coronavirus disease 2019 (COVID-19), it is strongly recommended to wear facemasks to minimize transmission risk. Wearing a facemask may have the potential to increase dyspnea and worsen cardiopulmonary parameters during exercise; however, research-based evidence is lacking. We investigated the hypothesis that wearing facemasks affects the sensation of dyspnea, pulse rate, and percutaneous arterial oxygen saturation during exercise. Healthy adults (15 men, 9 women) underwent a progressive treadmill test under 3 conditions in randomized order: wearing a surgical facemask, cloth facemask, or no facemask. Experiment was carried out once daily under each condition, for a total of 3 days. Each subject first sat on a chair for 30 minutes, then walked on a treadmill according to a Bruce protocol that was modified by us. The experiment was discontinued when the subject's pulse rate exceeded 174 beats/min. After discontinuation, the subject immediately sat on a chair and was allowed to rest for 10 minutes. Subjects were required to rate their levels of dyspnea perception on a numerical scale. Pulse rate and percutaneous arterial oxygen saturation were continuously monitored with a pulse oximeter. These parameters were recorded in each trial every 3 minutes after the start of the exercise; the point of discontinuation; and 5 and 10 minutes after discontinuation. The following findings were obtained. Wearing a facemask does not worsen dyspnea during light to moderate exercise but worsens dyspnea during vigorous exercise. Wearing a cloth facemask increases dyspnea more than wearing a surgical facemask during exercise and increases pulse rate during vigorous exercise, but it does not increase pulse rate during less vigorous exercise. Wearing a surgical facemask does not increase pulse rate at any load level. Lastly, wearing a facemask does not affect percutaneous arterial oxygen saturation during exercise at any load level regardless of facemask type.

Dataset Information

Functional Capacity in Patients Who Recovered from Mild COVID-19 with Exertional Dyspnea.

Background

Methods

Results

Conclusions

Publications

Functional Capacity in Patients Who Recovered from Mild COVID-19 with Exertional Dyspnea.

Similar Datasets

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