Tumor Suppressive Effects of GAS5 in Cancer Cells.
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ABSTRACT:
SUBMITTER: Kaur J
PROVIDER: S-EPMC9228804 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
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Tumor Suppressive Effects of GAS5 in Cancer Cells.
Kaur Jesminder J Salehen Nur'ain N Norazit Anwar A Rahman Amirah Abdul AA Murad Nor Azian Abdul NAA Rahman Nik Mohd Afizan Nik Abd NMANA Ibrahim Kamariah K
Non-coding RNA 20220528 3
In recent years, long non-coding RNAs (lncRNAs) have been shown to play important regulatory roles in cellular processes. Growth arrests specific transcript 5 (GAS5) is a lncRNA that is highly expressed during the cell cycle arrest phase but is downregulated in actively growing cells. Growth arrests specific transcript 5 was discovered to be downregulated in several cancers, primarily solid tumors, and it is known as a tumor suppressor gene that regulates cell proliferation, invasion, migration, ...[more]
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