Serum Phytosterols Are Not Associated with Inflammatory Markers in Two Cross-Sectional, Swiss Population-Based Studies (The CoLaus|PsyCoLaus Study).

ABSTRACT:

Background

The association between inflammation and dietary sterols remains poorly assessed at the population level.

Aims

To assess the possible association between serum levels of various phytosterols (PS) and inflammatory markers.

Methods

Serum levels of six PS (campesterol, campestanol, stigmasterol, sitosterol, sitostanol, brassicasterol), four cholesterol synthesis markers (lathosterol, lanosterol, desmosterol, dihydroxylanosterol) and one cholesterol absorption marker (cholestanol) were measured together with levels of CRP, IL-6 and TNF-α in two cross-sectional surveys of a population-based, prospective study.

Results

CRP levels were negatively associated with levels of cholestanol and of sterols of plant origin, although some associations were not statis

SUBMITTER: Stanasila L 

PROVIDER: S-EPMC9229848 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature