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Current Concepts and Future Trends in Increasing the Benefits of Cochlear Implantation: A Narrative Review.

ABSTRACT: Hearing loss is the most common neurosensory disorder, and with the constant increase in etiological factors, combined with early detection protocols, numbers will continue to rise. Cochlear implantation has become the gold standard for patients with severe hearing loss, and interest has shifted from implantation principles to the preservation of residual hearing following the procedure itself. As the audiological criteria for cochlear implant eligibility have expanded to include patients with good residual hearing, more attention is focused on complementary development of otoprotective agents, electrode design, and surgical approaches. The focus of this review is current aspects of preserving residual hearing through a summary of recent trends regarding surgical and pharmacological fundamentals. Subsequently, the assessment of new pharmacological options, novel bioactive molecules (neurotrophins, growth factors, etc.), nanoparticles, stem cells, and gene therapy are discussed.

SUBMITTER: Blebea CM

PROVIDER: S-EPMC9229893 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Current Concepts and Future Trends in Increasing the Benefits of Cochlear Implantation: A Narrative Review.

Blebea Cristina Maria CM Ujvary Laszlo Peter LP Necula Violeta V Dindelegan Maximilian George MG Perde-Schrepler Maria M Stamate Mirela Cristina MC Cosgarea Marcel M Maniu Alma Aurelia AA

Medicina (Kaunas, Lithuania) 20220531 6

Hearing loss is the most common neurosensory disorder, and with the constant increase in etiological factors, combined with early detection protocols, numbers will continue to rise. Cochlear implantation has become the gold standard for patients with severe hearing loss, and interest has shifted from implantation principles to the preservation of residual hearing following the procedure itself. As the audiological criteria for cochlear implant eligibility have expanded to include patients with g ...[more]

PMID: 35744010

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Current Concepts and Future Trends in Increasing the Benefits of Cochlear Implantation: A Narrative Review.

Publications

Current Concepts and Future Trends in Increasing the Benefits of Cochlear Implantation: A Narrative Review.

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