Porous Carbon Boosted Non-Enzymatic Glutamate Detection with Ultra-High Sensitivity in Broad Range Using Cu Ions.

ABSTRACT: A non-enzymatic electrochemical sensor, based on the electrode of a chitosan-derived carbon foam, has been successfully developed for the detection of glutamate. Attributed to the chelation of Cu ions and glutamate molecules, the glutamate could be detected in an amperometric way by means of the redox reactions of chelation compounds, which outperform the traditional enzymatic sensors. Moreover, due to the large electroactive surface area and effective electron transportation of the porous carbon foam, a remarkable electrochemical sensitivity up to 1.9 × 10⁴ μA/mM∙cm² and a broad-spectrum detection range from nM to mM scale have been achieved, which is two-orders of magnitude higher and one magnitude broader than the best reported values thus far. Furthermore, our rep

SUBMITTER: Ma Y 

PROVIDER: S-EPMC9230436 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature