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Beneath the Skin: A Review of Current Trends and Future Prospects of Transdermal Drug Delivery Systems.


ABSTRACT: The ideal drug delivery system has a bioavailability comparable to parenteral dosage forms but is as convenient and easy to use for the patient as oral solid dosage forms. In recent years, there has been increased interest in transdermal drug delivery (TDD) as a non-invasive delivery approach that is generally regarded as being easy to administer to more vulnerable age groups, such as paediatric and geriatric patients, while avoiding certain bioavailability concerns that arise from oral drug delivery due to poor absorbability and metabolism concerns. However, despite its many merits, TDD remains restricted to a select few drugs. The physiology of the skin poses a barrier against the feasible delivery of many drugs, limiting its applicability to only those drugs that possess physicochemical

SUBMITTER: Alkilani AZ 

PROVIDER: S-EPMC9231212 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature