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Evaluation of the prognostic value of lymphadenectomy for low-grade serous ovarian cancer: A case-control multicenter retrospective study.


ABSTRACT:

Background

The prognostic value of lymphadenectomy in low-grade serous ovarian cancer (LGSOC) remains uncertain.

Materials and methods

A retrospective analysis of 155 patients with LGSOC who underwent surgery over a ten-year period (2011-2020) was performed. The propensity score matching (PSM) algorithm was performed between the lymphadenectomy and no lymphadenectomy groups, and Kaplan-Meier analyses were conducted to evaluate clinical prognosis. Finally, univariate and multivariate Cox proportional hazards regression analyses were performed to analyze high-risk factors associated with clinical prognosis.

Results

In the pre-PSM cohort, 110 (71.0%) patients underwent lymphadenectomy. Of these, 54 (34.8%) experienced recurrence, and 27 (17.4%) died. There were statistic

SUBMITTER: Chen Z 

PROVIDER: S-EPMC9263964 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature