An Application of ITO Analysis in Secondary Kinship Identification.

ABSTRACT:

Objective

As the methods of the paternity and kinship testing have been developed, the second-degree and more distant relationships remain challenging in forensic science. Currently, the ITO method is the mainstream method to clarify the kinship between two individuals.

Methods

In this study, the ITO algorithm was used to calculate the uncle-nephew index based on 55 autosomal short tandem repeats (STRs) loci that were universally used for forensic identification. 19 STRs loci in Y chromosome were used for verification of the kinship.

Results

The cumulative uncle-nephew index between A and B was calculated to 0.993 by the analysis of the genotyping results of 21 STRs. When genotyping results of the other 34 STRs were added to the calculation algorithm, the cumulative u

SUBMITTER: Zhou P 

PROVIDER: S-EPMC9270131 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature