Review article: current and emerging therapies for the management of cirrhosis and its complications.

ABSTRACT:

Background

Cirrhosis is increasingly common and morbid. Optimal utilisation of therapeutic strategies to prevent and control the complications of cirrhosis are central to improving clinical and patient-reported outcomes.

Methods

We conducted a narrative review of the literature focusing on the most recent advances.

Results

We review the aetiology-focused therapies that can prevent cirrhosis and its complications. These include anti-viral therapies, psychopharmacological therapy for alcohol-use disorder, and the current landscape of clinical trials for non-alcoholic steatohepatitis. We review the current standard of care and latest developments in the management of hepatic encephalopathy (HE), ascites and hepatorenal syndrome. We evaluate the promise and drawbacks of c

SUBMITTER: Tapper EB 

PROVIDER: S-EPMC9314053 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature