Serial prostate magnetic resonance imaging fails to predict pathological progression in patients on active surveillance.

ABSTRACT:

Introduction

Limited data guide urological practice when employing prostate magnetic resonance imaging (MRI) in active surveillance (AS) protocols. To determine the ability of prostate MRI to predict pathological progression in AS patients, we correlated findings of serial MRI with results of surveillance biopsies.

Methods

Patients on AS with ≥2 prostate MRI and ≥2 prostate biopsies were included. Prostate Imaging-Reporting and Data System (PI-RADS) score upgrade, as assigned by experienced radiologists, was used to assess the ability of imaging to predict pathological biopsy progression. Imaging test statistics and the odds ratio of pathological progression according to MRI upgrade were calculated.

Results

Of 121 patients meeting criteria, 36 (30%) demonstrated MRI u

SUBMITTER: Omil-Lima D 

PROVIDER: S-EPMC9328855 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature