Low-dose ketamine infusions reduce opioid use in pediatric and young adult oncology patients.

ABSTRACT:

Background

Ketamine is an NMDA-receptor antagonist with analgesic and opioid-sparing properties. Although well studied in adults, more robust evidence supporting ketamine's use for pediatric pain management is needed. This retrospective study evaluates ketamine's opioid-sparing effectiveness in pediatric and young adult oncology and hematology patients.

Procedure

Continuous ketamine infusions administered for pain management between 2010-2020 were reviewed. Data including demographic characteristics, oncology/hematology and pain diagnoses, concurrent pain medications, and ketamine infusions' dose and duration were collected. Opioid consumption data based on delivery via patient-controlled analgesia were collected 1 day before (D1), all days during (cumulatively named D2), an

SUBMITTER: Anghelescu DL 

PROVIDER: S-EPMC9329174 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature