Association Between Early Left Ventricular Ejection Fraction Improvement After Transcatheter Aortic Valve Replacement and 5-Year Clinical Outcomes.

ABSTRACT:

Importance

In patients with severe aortic stenosis and left ventricular ejection fraction (LVEF) less than 50%, early LVEF improvement after transcatheter aortic valve replacement (TAVR) is associated with improved 1-year mortality; however, its association with long-term clinical outcomes is not known.

Objective

To examine the association between early LVEF improvement after TAVR and 5-year outcomes.

Design, setting, and participants

This cohort study analyzed patients enrolled in the Placement of Aortic Transcatheter Valves (PARTNER) 1, 2, and S3 trials and registries between July 2007 and April 2015. High- and intermediate-risk patients with baseline LVEF less than 50% who underwent transfemoral TAVR were included in the current study. Data were analyzed from Augus

SUBMITTER: Kolte D 

PROVIDER: S-EPMC9330296 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature