Combined Bacterial Meningitis and Infective Endocarditis: When Should We Search for the Other When Either One is Diagnosed?

ABSTRACT:

Introduction

We aimed to describe patients with coexisting infective endocarditis (IE) and bacterial meningitis (BM).

Methods

We merged two large prospective cohorts, an IE cohort and a BM cohort, with only cases of definite IE and community-acquired meningitis. We compared patients who had IE and BM concurrently to patients with IE only and BM only.

Results

Among the 1030 included patients, we identified 42 patients with IE-BM (4.1%). Baseline characteristics of patients with IE-BM were mostly similar to those of patients with IE, but meningitis was the predominant presentation at admission (39/42, 92.3%). Causative pathogens were predominantly Streptococcus pneumoniae (18/42, 42.9%) and Staphylococcus aureus (14/42, 33.3%). All pneumococcal IE were associated with B

SUBMITTER: Beraud G 

PROVIDER: S-EPMC9334461 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature