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The first invasive Candida auris infection in Taiwan.

ABSTRACT: Candida auris, a multidrug resistant pathogenic yeast, has spread worldwide and caused several outbreaks in healthcare settings. Here, we report the first case of C. auris candidemia in Taiwan in a patient with a two-month history of hospitalization in Vietnam. We performed further investigation on the isolate from the present case as well as the previously reported C. auris isolate identified from a wound in 2018 in Taiwan, which was the first case reported in Taiwan. Both C. auris isolates were found to be susceptible to fluconazole, amphotericin B, and echinocandins. Additionally, mutations in ERG11 or FKS1 were not detected in either isolate. Microsatellite genotyping revealed that both isolates belonged to the South Asian clade. In recent years, C. auris has emerged as a global concern, and differences in clades and susceptibility patterns mandate further awareness and systematic surveillance.

SUBMITTER: Tsai YT

PROVIDER: S-EPMC9336481 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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The first invasive Candida auris infection in Taiwan.

Tsai Yu-Te YT Lu Po-Liang PL Tang Hung-Jen HJ Huang Chung-Hao CH Hung Wei-Chun WC Tseng Yi-Ting YT Lee Kun-Mu KM Lin Shang-Yi SY

Emerging microbes & infections 20221201 1

Candida auris, a multidrug resistant pathogenic yeast, has spread worldwide and caused several outbreaks in healthcare settings. Here, we report the first case of C. auris candidemia in Taiwan in a patient with a two-month history of hospitalization in Vietnam. We performed further investigation on the isolate from the present case as well as the previously reported C. auris isolate identified from a wound in 2018 in Taiwan, which was the first case reported in Taiwan. Both ...[more]

PMID: 35811508

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