Poor outcomes in both infection and colonization with carbapenem-resistant Enterobacterales.

ABSTRACT:

Objectives

To describe the epidemiology of patients with nonintestinal carbapenem-resistant Enterobacterales (CRE) colonization and to compare clinical outcomes of these patients to those with CRE infection.

Design

A secondary analysis of Consortium on Resistance Against Carbapenems in Klebsiella and other Enterobacteriaceae 2 (CRACKLE-2), a prospective observational cohort.

Setting

A total of 49 US short-term acute-care hospitals.

Patients

Patients hospitalized with CRE isolated from clinical cultures, April, 30, 2016, through August 31, 2017.

Methods

We described characteristics of patients in CRACKLE-2 with nonintestinal CRE colonization and assessed the impact of site of colonization on clinical outcomes. We then compared outcomes of patients

SUBMITTER: Howard-Anderson JR 

PROVIDER: S-EPMC9343470 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature