Risk factors for severe PCR-positive SARS-CoV-2 infection in hospitalised children.

ABSTRACT:

Objective

To identify risk factors for severe disease in children hospitalised for SARS-CoV-2 infection.

Design

Multicentre retrospective cohort study.

Setting

18 hospitals in Canada, Iran and Costa Rica from 1 February 2020 to 31 May 2021.

Patients

Children<18 years of age hospitalised for symptomatic PCR-positive SARS-CoV-2 infection, including PCR-positive multisystem inflammatory syndrome in children (MIS-C).

Main outcome measure

Severity on the WHO COVID-19 Clinical Progression Scale was used for ordinal logistic regression analyses.

Results

We identified 403 hospitalisations. Median age was 3.78 years (IQR 0.53-10.77). At least one comorbidity was present in 46.4% (187/403) and multiple comorbidities in 18.6% (75/403). Eighty-one children (2

SUBMITTER: Schober T 

PROVIDER: S-EPMC9358955 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature