LI-RADS treatment response algorithm for detecting incomplete necrosis in hepatocellular carcinoma after locoregional treatment: a systematic review and meta-analysis using individual patient data.

ABSTRACT:

Purpose

To perform a systematic review and meta-analysis using individual patient data to investigate the diagnostic performance of Liver Imaging Reporting and Data System (LI-RADS) Treatment Response (TR) algorithm for detecting incomplete necrosis on pathology.

Methods

PubMed and EMBASE were searched from Jan 1, 2017 until October 14, 2020. Studies reporting diagnostic accuracy of LI-RADS TR algorithm on CT or MRI for detecting incomplete necrosis on pathology as a reference standard were included. Sensitivity and specificity were pooled using random-effects model. Subgroup analyses were performed for locoregional treatment (LRT) type and imaging modality.

Results

Six studies (393 patients, 534 lesions) were included. Pooled sensitivity was 0.56 (95% confidence inte

SUBMITTER: Kim TH 

PROVIDER: S-EPMC9358967 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature