Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study.

ABSTRACT:

Background

Better understanding of the association between characteristics of patients hospitalized with coronavirus disease 2019 (COVID-19) and outcome is needed to further improve upon patient management.

Methods

Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) is a prospective, observational study of 1164 patients from 20 hospitals across the United States. Disease severity was assessed using a 7-point ordinal scale based on degree of respiratory illness. Patients were prospectively surveyed for 1 year after discharge for post-acute sequalae of COVID-19 (PASC) through quarterly surveys. Demographics, comorbidities, radiographic findings, clinical laboratory values, SARS-CoV-2 PCR and serology were captured over a 28-day period. Multivariable logistic regression

SUBMITTER: Ozonoff A 

PROVIDER: S-EPMC9359694 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature