Correlation between 5-HTTLPR gene polymorphism and cognitive function of traumatic stress in Chinese Han children.

ABSTRACT:

Background

Post-traumatic stress disorder (PTSD) is a trauma-related psychological disorder with serious social and familial impacts. The involvement of 5-hydroxytryptamine transporter gene-linked polymorphic region (5-HTTLPR) in numerous mental disorders has been documented. This study explored the correlation between 5-HTTLPR gene polymorphism and cognitive function in Chinese Han children with PTSD.

Methods

A total of 60 PTSD children treated from December 2019 to December 2021 were selected as study participants, with another 60 healthy children selected as controls. We assessed the cognitive function of participants using the Mini-Mental State Examination (MMSE). Additionally, the PTSD level was estimated by the Children's Revised Impact of Event Scale (CR

SUBMITTER: Wu M 

PROVIDER: S-EPMC9360820 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature