Anterior hilum anastomosis versus posterior hilum anastomosis in a mouse lung transplantation model.

ABSTRACT:

Objectives

The mouse orthotopic lung transplantation (LTx) model is of enormous research value in lung transplantation. This study compares 2 anastomotic methods (anterior and posterior hilum anastomosis) of mouse LTx in term of difficulty, operation time, and postoperative effects.

Methods

Twenty mice received LTx with slipknots for anterior hilum anastomosis (AH group), and 28 received LTx with a microvessel clip for posterior hilum anastomosis (PH group), all by a single surgeon. The operation time was recorded and the grafts were evaluated 24 hours after surgery.

Results

The success rates in the recipient animals were 85% (17/20) in AH group and 89% (25/28) in PH group (P > .05). The recipient operation time and back table time in AH group were longer than

SUBMITTER: Zhao J 

PROVIDER: S-EPMC9366536 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature