Lower SARS-CoV-2 Seroprevalence among Cancer Patients in Sub-Saharan Africa.

ABSTRACT:

Background

Despite the high COVID-19 morbidity and mortality rates across the world, the reported rates in sub-Saharan Africa (SSA), which has a higher burden of other infectious diseases and overwhelmed healthcare systems, remain relatively low. This study aims to better understand the potential factors that contribute to this phenomenon, especially among cancer patients who are considered as a high-risk group for developing severe COVID-19.

Methods

Plasma samples collected during the COVID-19 pandemic from SARS-CoV-2 unvaccinated cancer and potential blood donor populations were analyzed for SARS-CoV-2 (spike and nucleocapsid proteins) antibodies by an immunofluorescence assay. The relationships between SARS-CoV-2 seroprevalences and study variables were determined using a

SUBMITTER: Tso FY 

PROVIDER: S-EPMC9369079 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature