Influence of acetate- vs. lactate-containing fluid bolus therapy on acid-base status, electrolytes, and plasma lactate in dogs.

ABSTRACT:

Objective

Acetate- and lactate-containing fluids influence the acid-base and electrolyte status. This prospective, randomized, clinical study compared two balanced crystalloid solutions regarding their influence on acid-base status, electrolytes, and lactate values, when given to dogs as a resuscitation bolus of 30 mL/kg.

Material and methods

One hundred client-owned dogs presenting to the emergency service with signs of fluid deficits were randomly assigned to receive an intravenous bolus of 30 mL/kg of either a lactate- (LAC), or an acetate-containing solution (ACET). Before and after the bolus, vital parameters were assessed, and a venous blood gas analysis was performed.

Results

Both solutions performed equally well in decreasing the heart rate (ACET: -10 ± 27 bpm

SUBMITTER: Klein-Richers U 

PROVIDER: S-EPMC9372486 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature