Ventilatory efficiency is superior to peak oxygen uptake for prediction of lung resection cardiovascular complications.

ABSTRACT:

Introduction

Ventilatory efficiency (VE/VCO2 slope) has been shown superior to peak oxygen consumption (VO2) for prediction of post-operative pulmonary complications in patients undergoing thoracotomy. VE/VCO2 slope is determined by ventilatory drive and ventilation/perfusion mismatch whereas VO2 is related to cardiac output and arteriovenous oxygen difference. We hypothesized pre-operative VO2 predicts post-operative cardiovascular complications in patients undergoing lung resection.

Methods

Lung resection candidates from a published study were evaluated by post-hoc analysis. All of the patients underwent preoperative cardiopulmonary exercise testing. Post-operative cardiovascular complications were assessed during the first 30 post-operative days or hospital stay. One-way

SUBMITTER: Mazur A 

PROVIDER: S-EPMC9374210 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature