Ontology highlight
ABSTRACT:
SUBMITTER: Liu J
PROVIDER: S-EPMC9378665 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Nature communications 20220815 1
Conformational isomerization can be guided by weak interactions such as chalcogen bonding (ChB) interactions. Here we report a catalytic strategy for asymmetric access to chiral sulfoxides by employing conformational isomerization and chalcogen bonding interactions. The reaction involves a sulfoxide bearing two aldehyde moieties as the substrate that, according to structural analysis and DFT calculations, exists as a racemic mixture due to the presence of an intramolecular chalcogen bond. This c ...[more]