Life-Threatening Complications of Influenza vs Coronavirus Disease 2019 (COVID-19) in US Children.

ABSTRACT:

Background

Clinical differences between critical illness from influenza infection vs coronavirus disease 2019 (COVID-19) have not been well characterized in pediatric patients.

Methods

We compared demographics, clinical characteristics, and outcomes of US children (aged 8 months to 17 years) admitted to the intensive care or high-acuity unit with influenza or COVID-19. Using mixed-effects models, we assessed the odds of death or requiring life support for influenza vs COVID-19 after adjustment for age, sex, race and Hispanic origin, and underlying conditions including obesity.

Results

Children with influenza (n = 179) were younger than those with COVID-19 (n = 381; median, 5.2 years vs 13.8 years), less likely to be non-Hispanic Black (14.5% vs 27.6%) or Hispanic (24.

SUBMITTER: Halasa NB 

PROVIDER: S-EPMC9384330 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature