Hawthorn fruit acid consumption attenuates hyperlipidemia-associated oxidative damage in rats.

ABSTRACT:

Context

Hyperlipidemia is a highly prevalent risk factor for atherosclerosis and stroke. The currently available medications used to treat Hyperlipidemia cannot improve its oxidative stress damage. Consumption of hawthorn can regulate blood sugar and blood lipids, and its rich fruit acid is a natural antioxidant that can improve oxidative stress damage.

Objective

The present research aimed to investigate the protective effect of hawthorn fruit acid (HFA) on hyperlipidemia and to determine its potential molecular mechanism.

Materials and methods

Sprague-Dawley rats were fed a high-fat diet (HFD) to induce hyperlipidemia and treated orally with hawthorn fruit acids (HFA). Serum and liver levels of total cholesterol (TC), triglycerides (TG), high-density lipoprotein chol

SUBMITTER: Feng Y 

PROVIDER: S-EPMC9384962 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature