Verbal manipulations of learning expectancy do not enhance reconsolidation.

ABSTRACT:

Objectives

Pharmacological studies using propranolol suggest that if reactivation signals that new information will be learned (i.e., there is an expectation for learning) reconsolidation can be enhanced. We examined if the verbal instructions to expect new learning will enhance reconsolidation of fear memories using the post-retrieval extinction paradigm.

Methods

On day one, participants (n = 48) underwent differential fear conditioning to two images (CS+ and CS-). On day two, participants were randomly assigned to one of three groups; groups one and two had their memory for the CS+ reactivated (i.e., a single presentation of the CS+) 10 minutes prior to extinction, whereas group three did not have their memory reactivated but went right to extinction (no reactivation group

SUBMITTER: Marinos J 

PROVIDER: S-EPMC9387781 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature