Prediction error demarcates the transition from retrieval, to reconsolidation, to new learning.

ABSTRACT: Although disrupting reconsolidation is promising in targeting emotional memories, the conditions under which memory becomes labile are still unclear. The current study showed that post-retrieval changes in expectancy as an index for prediction error may serve as a read-out for the underlying processes engaged by memory reactivation. Minor environmental changes define whether retrieval induces memory reconsolidation or the initiation of a new memory trace even before fear extinction can be observed.

SUBMITTER: Sevenster D 

PROVIDER: S-EPMC4201815 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature