Toxoplasmosis in patients with an autoimmune disease and immunosuppressive agents: A multicenter study and literature review.

ABSTRACT:

Background

Cases of Toxoplasma reactivation or more severe primary infection have been reported in patients receiving immunosuppressive (IS) treatment for autoimmune diseases (AID). The purpose of this study was to describe features of toxoplasmosis occurring in patients with AID treated by IS therapy, excluded HIV-positive and transplant patients.

Methods

A multicenter descriptive study was conducted using data from the French National Reference Center for Toxoplasmosis (NRCT) that received DNA extracts or strains isolated from patients, associated with clinical data. Other cases were retrieved through a questionnaire sent to all French parasitology and internal medicine departments. Furthermore, a systematic literature review was conducted.

Results

61 cases were col

SUBMITTER: Durieux MF 

PROVIDER: S-EPMC9387931 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature