Impact of tricuspid valve insufficiency on the performance of left ventricular assist devices.

ABSTRACT:

Objective

To evaluate the impact of severe tricuspid valve insufficiency (TVI) at the time of left ventricular assist device (LVAD) implantation on the hemodynamic and LVAD parameters in an acute ovine model.

Methods

Stable heart failure (HF) was induced in 10 ovines through the application of 3 ± 1 coronary ligations. Once stable HF was obtained (after 15 ± 5 days), the animals were supported with an LVAD. Hemodynamic data and pump parameters were obtained and compared in 2 settings; first with LVAD in place after weaning from the cardiopulmonary bypass machine (no TVI condition) and second following the induction of severe TVI through resection of the tricuspid valve (TVI condition).

Results

There were no statistically significant differences in the hemodynamic and

SUBMITTER: Gomez Hamacher CJR 

PROVIDER: S-EPMC9390470 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature