Accelerated dual-venc 4D flow MRI with variable high-venc spatial resolution for neurovascular applications.

ABSTRACT:

Purpose

Dual-velocity encoded (dual-venc or DV) 4D flow MRI achieves wide velocity dynamic range and velocity-to-noise ratio (VNR), enabling accurate neurovascular flow characterization. To reduce scan time, we present interleaved dual-venc 4D Flow with independently prescribed, prospectively undersampled spatial resolution of the high-venc (HV) acquisition: Variable Spatial Resolution Dual Venc (VSRDV).

Methods

A prototype VSRDV sequence was developed based on a Cartesian acquisition with eight-point phase encoding, combining PEAK-GRAPPA acceleration with zero-filling in phase and partition directions for HV. The VSRDV approach was optimized by varying z, the zero-filling fraction of HV relative to low-venc, between 0%-80% in vitro (realistic neurovascular model with pulsat

SUBMITTER: Aristova M 

PROVIDER: S-EPMC9392495 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature