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Convenient design method for customized implants based on bionic vein structure features.

ABSTRACT: Matching implants to bones is crucial for customized orthopedic medicine. Existing methods for designing customized implants predominantly adopt the parameterized deformation method that uses a fragmented representation of semantic parameters. Such a representation cannot provide information integration management and therefore restricts the retrieval of information regarding implant features and the improvement of customized design efficiency. Therefore, this study proposes a rapid design method for customized implants based on bionic vein structure features. First, a bionic vein structure was designed to represent the implant type. Second, the bionic vein structure was represented by a digraph structure with morphological and dimensional features. Finally, the implant model was rapidly built by retrieving the sketch and other modeling operations. Common implants such as the T-shaped plate, L-shaped plate, clover plate, and femoral stem prosthesis were used as explanations or test cases. The experimental work shows that combining the traditional parametric deformation method with bionic vein structure features in our present method is flexible and efficient results, and can improve the efficiency of customized implant design.

SUBMITTER: Wang L

PROVIDER: S-EPMC9412103 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Convenient design method for customized implants based on bionic vein structure features.

Wang Lin L Geng Weizhong W He Kunjin K Guo Kaijin K

Frontiers in bioengineering and biotechnology 20220812

Matching implants to bones is crucial for customized orthopedic medicine. Existing methods for designing customized implants predominantly adopt the parameterized deformation method that uses a fragmented representation of semantic parameters. Such a representation cannot provide information integration management and therefore restricts the retrieval of information regarding implant features and the improvement of customized design efficiency. Therefore, this study proposes a rapid design metho ...[more]

PMID: 36032731

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Project description:BackgroundThree groups of iris prostheses can be distinguished for the surgical treatment of iris defects: (1) segmental iris implants, (2) combined iris diaphragm intraocular lenses (IOL) and (3) pure iris implants. Most iris reconstructions are accompanied by aphakia correction with secondary IOL implantation. Although the primary goal is to create a pupil and to improve glare perception, contrast sensitivity and visual acuity, the esthetic result is also a relevant component.ObjectiveFunctional and esthetic results after replacement of an aniridia IOL implant with a custom-made artificial iris with IOL.Material and methodsIn this retrospective study with seven eyes from seven patients, an iris diaphragm IOL (Morcher GmbH, Stuttgart, Germany) was exchanged for medical reasons (subluxation) against a custom-made artificial iris made of silicone (ArtificialIris, HumanOptics, Erlangen, Germany) in combination with a sutured IOL. The follow-up period was at least 3 months. Best corrected distance visual acuity (BCVA), endothelial cell count (ECC), complications, glare perception as well as esthetic outcome and patient satisfaction were evaluated.ResultsThe BCVA and ECC showed no statistically significant change between the preoperative and postoperative values (p > 0.05). There was a decentration of the iris IOL implant of 0.27 ± 0.19 mm three months postoperatively. On a visual analogue scale (VAS) from 1 to 10 (1 = not satisfied at all, 10 = extremely satisfied), satisfaction with the overall result was rated 8.6 ± 2.5. Subjective glare perception improved to 5.6 ± 3.5 and subjective esthetic impairment improved to 2.4 ± 2.0 on the VAS (1 = none, 10 = extremely strong). Postoperative complications included transient intraocular hypotonia in two eyes, intraocular pressure increase in two eyes, retinal detachment and transient vitreous hemorrhage in one eye each. Of the seven patients six would repeat the procedure.ConclusionCompared to a rigid aniridia IOL implant, replacement with a custom-made artificial iris in combination with an IOL provides not only a good functional result but simultaneously also an esthetically pleasing result.

Project description:HypothesisA novel smartphone-based software application can facilitate self-selection of frequency allocation tables (FAT) in postlingually deaf cochlear implant (CI) users.BackgroundCIs use FATs to represent the tonotopic organization of a normal cochlea. Current CI fitting methods typically use a standard FAT for all patients regardless of individual differences in cochlear size and electrode location. In postlingually deaf patients, different amounts of mismatch can result between the frequency-place function they experienced when they had normal hearing and the frequency-place function that results from the standard FAT. For some CI users, an alternative FAT may enhance sound quality or speech perception. Currently, no widely available tools exist to aid real-time selection of different FATs. This study aims to develop a new smartphone tool for this purpose and to evaluate speech perception and sound quality measures in a pilot study of CI subjects using this application.MethodsA smartphone application for a widely available mobile platform (iOS) was developed to serve as a preprocessor of auditory input to a clinical CI speech processor and enable interactive real-time selection of FATs. The application's output was validated by measuring electrodograms for various inputs. A pilot study was conducted in six CI subjects. Speech perception was evaluated using word recognition tests.ResultsAll subjects successfully used the portable application with their clinical speech processors to experience different FATs while listening to running speech. The users were all able to select one table that they judged provided the best sound quality. All subjects chose a FAT different from the standard FAT in their everyday clinical processor. Using the smartphone application, the mean consonant-nucleus-consonant score with the default FAT selection was 28.5% (SD 16.8) and 29.5% (SD 16.4) when using a self-selected FAT.ConclusionA portable smartphone application enables CI users to self-select frequency allocation tables in real time. Even though the self-selected FATs that were deemed to have better sound quality were only tested acutely (i.e., without long-term experience with them), speech perception scores were not inferior to those obtained with the clinical FATs. This software application may be a valuable tool for improving future methods of CI fitting.

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Convenient design method for customized implants based on bionic vein structure features.

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Convenient design method for customized implants based on bionic vein structure features.

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