Impact of Helicobacter pylori eradication timing on the risk of thromboembolism events in patients with peptic ulcer disease: a population-based cohort study.

ABSTRACT:

Objectives

To evaluate the impact of Helicobacter pylori eradication on venous thromboembolism (VTE) events, and the differences between early and late treatment timing.

Design

A population-based cohort study.

Setting

Taiwan's National Health Insurance Research Database.

Participants

A total of 6736 patients who received H. pylori eradication therapy from 2000 to 2010 were identified. We randomly selected 26 944 subjects matching in gender, age and baseline year as comparison cohort.

Primary and secondary outcome measures

The incidence rate ratios of VTE in the H. pylori eradication cohorts to that of the control cohort were examined. Multivariable Cox proportional hazard regression analysis was used to estimate the relative HRs and

SUBMITTER: Lai JN 

PROVIDER: S-EPMC9413183 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature